The Closure of Patent Foramen Ovale in Preventing Subsequent Neurological Events: A Bayesian Network Meta-Analysis to Identify the Best Device | Zendy

L Varotto | Zendy; Gianni Bregolin | Zendy; Mariemma Paccanaro | Zendy; Antonella Boni | Zendy; Carlo Bonanno | Zendy; Francesco Perini | Zendy

Open Access

The Closure of Patent Foramen Ovale in Preventing Subsequent Neurological Events: A Bayesian Network Meta-Analysis to Identify the Best Device

Author(s) -

L Varotto,

Gianni Bregolin,

Mariemma Paccanaro,

Antonella Boni,

Carlo Bonanno,

Francesco Perini

Publication year - 2020

Publication title -

cerebrovascular diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.221

H-Index - 104

eISSN - 1421-9786

pISSN - 1015-9770

DOI - 10.1159/000507317

Subject(s) - medicine , patent foramen ovale , randomized controlled trial , meta analysis , stroke (engine) , atrial fibrillation , percutaneous , cardiology , surgery , mechanical engineering , engineering

Randomized-controlled trials (RCTs) reported a finding on the safety and efficacy of percutaneous patent foramen ovale (PFO) closure to prevent stroke recurrence. It showed that the Amplatzer (AMP) device appears to be superior to medical therapy (MT) in preventing strokes and episodes of atrial fibrillation (AF), than other devices. We performed a network meta-analysis (NMA) to evaluate the closure of PFO in preventing subsequent neurological events while investigating the results obtained by specific devices.

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