Carcinoid Heart Disease: Prognostic Value of 5-Hydroxyindoleacetic Acid Levels and Impact on Survival: A Systematic Literature Review | Zendy

Amy Buchanan-Hughes | Zendy; A Pashley | Zendy; Marion Feuilly | Zendy; Florence Marteau | Zendy; D. Mark Pritchard | Zendy; Simron Singh | Zendy

Open Access

Carcinoid Heart Disease: Prognostic Value of 5-Hydroxyindoleacetic Acid Levels and Impact on Survival: A Systematic Literature Review

Author(s) -

Amy Buchanan-Hughes,

A Pashley,

Marion Feuilly,

Florence Marteau,

D. Mark Pritchard,

Simron Singh

Publication year - 2020

Publication title -

neuroendocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.493

H-Index - 101

eISSN - 1423-0194

pISSN - 0028-3835

DOI - 10.1159/000506744

Subject(s) - medicine , carcinoid syndrome , incidence (geometry) , gastroenterology , meta analysis , disease , carcinoid heart disease , odds ratio , hormone , endocrinology , physics , optics

Carcinoid heart disease (CHD) can develop in patients with carcinoid syndrome (CS), itself caused by overproduction of hormones and other products from some neuroendocrine tumours. The most common hormone is serotonin, detected as high 5-hydroxyindoleacetic acid (5-HIAA). This systematic literature review summarises current literature on the impact of CHD on survival, and the relationship between 5-HIAA levels and CHD development, progression, and mortality.

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