Ghrelin Gene Polymorphisms in Irritable Bowel Syndrome | Zendy

Theodora Kalli | Zendy; Tilemachos Koutouratsas | Zendy; George Karamanolis | Zendy; Maria Gazouli | Zendy

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Ghrelin Gene Polymorphisms in Irritable Bowel Syndrome

Author(s) -

Theodora Kalli,

Tilemachos Koutouratsas,

George Karamanolis,

Maria Gazouli

Publication year - 2020

Publication title -

digestion

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.882

H-Index - 75

eISSN - 1421-9867

pISSN - 0012-2823

DOI - 10.1159/000506306

Subject(s) - irritable bowel syndrome , genotype , gastroenterology , ghrelin , medicine , pathogenesis , genotyping , constipation , allele , allele frequency , polymorphism (computer science) , diarrhea , genotype frequency , endocrinology , hormone , biology , genetics , gene

Irritable bowel syndrome (IBS) is a bowel disorder characterized by pain accompanying defecation or altered bowel habits, divided into diarrhea-predominant, constipation-predominant, and alternating subtypes, whose pathogenesis is considered to include disordered bowel motility. The hormone ghrelin is a growth hormone secretagogue which furthermore affects gastrointestinal motility. We study the association between its genetic polymorphisms and the risk for IBS.

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