Next Generation Sequencing-Based Fetal ABO Blood Group Prediction by Analysis of Cell-Free DNA from Maternal Plasma | Zendy

Klaus Rieneck | Zendy; Christoffer Hother | Zendy; Frederik Banch Clausen | Zendy; Marianne Antonius Jakobsen | Zendy; Thomas Bergholt | Zendy; Ellinor Hellmuth | Zendy; Lene Grønbeck | Zendy; Morten Hanefeld Dziegiel | Zendy

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Next Generation Sequencing-Based Fetal ABO Blood Group Prediction by Analysis of Cell-Free DNA from Maternal Plasma

Author(s) -

Klaus Rieneck,

Christoffer Hother,

Frederik Banch Clausen,

Marianne Antonius Jakobsen,

Thomas Bergholt,

Ellinor Hellmuth,

Lene Grønbeck,

Morten Hanefeld Dziegiel

Publication year - 2020

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000505464

Subject(s) - abo blood group system , concordance , fetus , cell free fetal dna , serology , obstetrics , biology , dna sequencing , pregnancy , prenatal diagnosis , antibody , primer (cosmetics) , medicine , immunology , andrology , genetics , dna , chemistry , organic chemistry

ABO blood group incompatibility between a pregnant woman and her fetus as a cause of morbidity or mortality of the fetus or newborn remains an important, albeit rare, risk. When a pregnant woman has a high level of anti-A or anti-B IgG antibodies, the child may be at risk for hemolytic disease of the fetus and newborn (HDFN). Performing a direct prenatal determination of the fetal ABO blood group can provide valuable clinical information.

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