Effects of Receptor for Advanced Glycation End-Products (RAGE) Signaling on Intestinal Ischemic Damage in Mice | Zendy

Yurika Makino | Zendy; Shinya Munakata | Zendy; Takae Ueyama | Zendy; Kumpei Honjo | Zendy; Shingo Kawano | Zendy; Makoto Takahashi | Zendy; Yutaka Kojima | Zendy; Yuichi Tomiki | Zendy; Kazuhiro Sakamoto | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effects of Receptor for Advanced Glycation End-Products (RAGE) Signaling on Intestinal Ischemic Damage in Mice

Author(s) -

Yurika Makino,

Shinya Munakata,

Takae Ueyama,

Kumpei Honjo,

Shingo Kawano,

Makoto Takahashi,

Yutaka Kojima,

Yuichi Tomiki,

Kazuhiro Sakamoto

Publication year - 2019

Publication title -

european surgical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.658

H-Index - 46

eISSN - 1421-9921

pISSN - 0014-312X

DOI - 10.1159/000504751

Subject(s) - glycation , rage (emotion) , receptor , advanced glycation end product , signal transduction , ischemic injury , medicine , immunology , chemistry , endocrinology , biology , microbiology and biotechnology , ischemia , neuroscience

Superior mesenteric artery ischemia and nonocclusive mesenteric ischemia are representative diseases of the vascular emergency known as irreversible transmural intestinal necrosis (ITIN). The receptor for advanced glycation end-products (RAGE) belongs to the immunoglobulin superfamily of extracellular ligands, which also includes high-mobility group box 1 (HMGB-1) and proteins of the S100 family. The HMGB-1 ligands have been implicated in the pathogenesis of various inflammatory disorders. This study was designed to investigate the relation between RAGE and ITIN in a murine acute intestinal ischemic model.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research