Protective Effect of Diphenhydramine against Traumatic Brain Injury in Rats via Modulation of Oxidative Stress and Inflammation | Zendy

Wenyong Pan | Zendy; Zhigang Cao | Zendy; Dongyang Liu | Zendy; Yingbin Jiao | Zendy

Open Access

Protective Effect of Diphenhydramine against Traumatic Brain Injury in Rats via Modulation of Oxidative Stress and Inflammation

Author(s) -

Wenyong Pan,

Zhigang Cao,

Dongyang Liu,

Yingbin Jiao

Publication year - 2019

Publication title -

pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.51

H-Index - 59

eISSN - 1423-0313

pISSN - 0031-7012

DOI - 10.1159/000502767

Subject(s) - oxidative stress , neuroprotection , malondialdehyde , inflammation , pharmacology , medicine , superoxide dismutase , traumatic brain injury , lipid peroxidation , glutathione peroxidase , glutathione , neuroinflammation , endocrinology , chemistry , biochemistry , enzyme , psychiatry

Traumatic brain injury (TBI) is considered a major burden across the globe affecting both individuals and their families. Therefore, the present study was conducted to determine the protective effect of diphenhydramine (DPM) against TBI in experimental rats.

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