Current Insights into the Role of the Growth Hormone-Insulin-Like Growth Factor System in Short Children Born Small for Gestational Age
Author(s) -
Judith S. Renes,
Jaap van Doorn,
Anita C. S. HokkenKoelega
Publication year - 2019
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000502739
Subject(s) - small for gestational age , short stature , endocrinology , medicine , growth factor , insulin like growth factor , cord blood , placenta , somatomedin , in utero , growth hormone , growth hormone treatment , insulin like growth factor binding protein , hormone , gestational age , biology , pregnancy , receptor , fetus , genetics
The reason for the insufficient catch-up growth seen in 10% of children born small for gestational age (SGA) is poorly understood. Disturbances in the growth hormone (GH) - insulin-like growth factor (IGF) axis might underlie this failure to show sufficient catch-up growth.
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