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Tofacitinib as Induction and Maintenance Therapy in Japanese Patients with Active Ulcerative Colitis
Author(s) -
Yasuo Suzuki,
Mamoru Watanabe,
Toshiyuki Matsui,
Satoshi Motoya,
Tadakazu Hisamatsu,
Hirotoshi Yuasa,
Junichi Tabira,
Naoki Isogawa,
Shinichi Tsuchiwata,
Shoko Arai,
Toshifumi Hibi∥
Publication year - 2019
Publication title -
inflammatory intestinal diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9403
pISSN - 2296-9365
DOI - 10.1159/000502144
Subject(s) - tofacitinib , medicine , ulcerative colitis , placebo , gastroenterology , janus kinase inhibitor , adverse effect , clinical endpoint , population , clinical trial , rheumatoid arthritis , alternative medicine , disease , environmental health , pathology
Tofacitinib is an oral, small molecule Janus kinase inhibitor approved in Japan for the treatment of ulcerative colitis (UC). Differences in the safety profile of tofacitinib in Japanese patients versus the global population, such as a higher risk of herpes zoster, have been reported.

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