Distribution of Neuroendocrine Marker-Positive Cells in Colorectal Cancer Tissue and Normal Mucosal Tissue: Consideration of Histogenesis of Neuroendocrine Cancer
Author(s) -
Takashi Ogimi,
Sotaro Sadahiro,
Yutaro Kamei,
Lin Fung Chan,
Hiroshi Miyakita,
Gota Saito,
Kazutake Okada,
Toshiyuki Suzuki,
Hiroshi Kajiwara
Publication year - 2019
Publication title -
oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.987
H-Index - 98
eISSN - 1423-0232
pISSN - 0030-2414
DOI - 10.1159/000501521
Subject(s) - histogenesis , chromogranin a , synaptophysin , colorectal cancer , adenocarcinoma , pathology , neuroendocrine differentiation , rectum , cancer , medicine , immunohistochemistry , prostate cancer
Colorectal neuroendocrine carcinoma (NEC) is a rare disease, and mixed cases with colorectal adenocarcinoma also exist. The histogenesis of this disease remains unclear. We studied the numbers of neuroendocrine marker-positive cells in adenocarcinoma tissue and in normal -mucosal tissue to investigate the relation between adenocarcinoma and NEC and to discuss the histogenesis of NEC.
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