Can Oral Fesoterodine Be an Alternative for Intravesical Oxybutynin Instillations in Children with Neuropathic Bladder Dysfunction? | Zendy

Marleen van den Heijkant | Zendy; Katrien De Coster | Zendy; Katrien Jansen | Zendy; Guy Bogaert | Zendy

Open Access

Can Oral Fesoterodine Be an Alternative for Intravesical Oxybutynin Instillations in Children with Neuropathic Bladder Dysfunction?

Author(s) -

Marleen van den Heijkant,

Katrien De Coster,

Katrien Jansen,

Guy Bogaert

Publication year - 2019

Publication title -

urologia internationalis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.771

H-Index - 53

eISSN - 1423-0399

pISSN - 0042-1138

DOI - 10.1159/000499757

Subject(s) - oxybutynin , medicine , anticholinergic , urology , urination , anesthesia , urinary system , overactive bladder , alternative medicine , pathology

A low-pressure bladder in children with neuropathic bladder dysfunction can be achieved using anticholinergic medication. Due to the significant side effects of oral oxybutynin, our patients are treated with daily intravesical oxybutynin instillations. Newer oral anticholinergic medication, such as fesoterodine, claim to have fewer side effects in a once daily formulation. Because once-daily oral intake is easier than performing twice-daily intravesical instillations, we studied the effects of switching from intravesical oxybutynin to oral fesoterodine and compared the clinical response, urodynamic parameters and side effects.

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