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Decreased Spontaneous Brain Activity and Functional Connectivity in Type 1 Diabetic Patients Without Microvascular Complications
Author(s) -
Wenqing Xia,
YuChen Chen,
Yong Luo,
Danfeng Zhang,
Huiyou Chen,
Jianhua Ma,
Xindao Yin
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000495960
Subject(s) - functional magnetic resonance imaging , default mode network , medicine , posterior cingulate , resting state fmri , audiology , cognition , functional connectivity , magnetic resonance imaging , superior frontal gyrus , anterior cingulate cortex , brain activity and meditation , cardiology , type 1 diabetes , diabetes mellitus , neuroscience , endocrinology , psychology , psychiatry , electroencephalography , radiology
Type 1 diabetes mellitus (T1DM) has been proven to be associated with an increased risk of cognitive dysfunction. In this study, we aimed to investigate whether disrupted spontaneous activity and functional connectivity (FC) exist in T1DM patients using resting-state functional magnetic resonance imaging (rs-fMRI) and to detect the relationships of these parameters with cognitive impairment.

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