Involvement of the TLR4/NF-κB Signaling Pathway in the Repair of Esophageal Mucosa Injury in Rats with Gastroesophageal Reflux Disease | Zendy

Haixiang Yu | Zendy; Xiaolong Wang | Zendy; Le-Ning Zhang | Zendy; Ji Zhang | Zendy; Wei Zhao | Zendy

Open Access

Involvement of the TLR4/NF-κB Signaling Pathway in the Repair of Esophageal Mucosa Injury in Rats with Gastroesophageal Reflux Disease

Author(s) -

Haixiang Yu,

Xiaolong Wang,

Le-Ning Zhang,

Ji Zhang,

Wei Zhao

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000495652

Subject(s) - gerd , tbars , tunel assay , tlr4 , apoptosis , proinflammatory cytokine , nf κb , signal transduction , pathology , medicine , biology , oxidative stress , chemistry , immunohistochemistry , reflux , inflammation , lipid peroxidation , microbiology and biotechnology , disease , biochemistry

Numerous studies have highlighted the activation of NF-κB in the esophageal mucosa during the early stages of gastroesophageal reflux disease (GERD). The present study aimed to investigate the role of the TLR4/NF-κB signaling pathway in GERD rat models.

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