Galangin Alleviates Liver Ischemia-Reperfusion Injury in a Rat Model by Mediating the PI3K/AKT Pathway | Zendy

Yang Li | Zendy; Liquan Tong | Zendy; Jingyan Zhang | Zendy; Yafeng Zhang | Zendy; Feng Zhang | Zendy

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Galangin Alleviates Liver Ischemia-Reperfusion Injury in a Rat Model by Mediating the PI3K/AKT Pathway

Author(s) -

Yang Li,

Liquan Tong,

Jingyan Zhang,

Yafeng Zhang,

Feng Zhang

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000495553

Subject(s) - pi3k/akt/mtor pathway , protein kinase b , ischemia , galangin , medicine , reperfusion injury , signal transduction , biology , microbiology and biotechnology , biochemistry , kaempferol , antioxidant , quercetin

Liver ischemia-reperfusion (I/R) injury is a pathological process that often occurs during liver and trauma surgery. There are numerous causes of liver I/R injury, but the mechanism is unknown. Galangin (GA) is a flavonoid, a polyphenolic compound widely distributed in medicinal herbs that has anti-inflammatory, antioxidant, and antitumor activity. This study evaluated the protective effect of GA on hepatic I/R injury.

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