Characterization of the Hippocampal Neuroimmune Response to Binge-Like Ethanol Consumption in the Drinking in the Dark Model | Zendy

Isabella R. Grifasi | Zendy; Scot McIntosh | Zendy; Rhian Thomas | Zendy; Donald T. Lysle | Zendy; Todd E. Thiele | Zendy; S. Alex Marshall | Zendy

Open Access

Characterization of the Hippocampal Neuroimmune Response to Binge-Like Ethanol Consumption in the Drinking in the Dark Model

Author(s) -

Isabella R. Grifasi,

Scot McIntosh,

Rhian Thomas,

Donald T. Lysle,

Todd E. Thiele,

S. Alex Marshall

Publication year - 2019

Publication title -

neuroimmunomodulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.635

H-Index - 65

eISSN - 1423-0216

pISSN - 1021-7401

DOI - 10.1159/000495210

Subject(s) - astrocyte , binge drinking , hippocampus , hippocampal formation , endocrinology , medicine , ethanol , cytokine , proinflammatory cytokine , psychology , central nervous system , chemistry , alcohol , alcohol consumption , inflammation , biochemistry

Alcohol dependence leads to dysregulation of the neuroimmune system, but the effects of excessive alcohol consumption on key players of the neuroimmune response after episodic binge drinking in nondependence has not been readily assessed. These studies seek to determine how the neuroimmune system within the hippocampus responds to binge-like consumption prior to dependence or evidence of brain damage.

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