Loss of Transfected Human Brain Micro-Vascular Endothelial Cell Integrity during Herpes Simplex Virus Infection | Zendy

Sau Har Lee | Zendy; Nadia Atiya | Zendy; Seok Mui Wang | Zendy; Rishya Manikam | Zendy; Chandramathi Samudi Raju | Zendy; Shamala Devi Sekaran | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Loss of Transfected Human Brain Micro-Vascular Endothelial Cell Integrity during Herpes Simplex Virus Infection

Author(s) -

Sau Har Lee,

Nadia Atiya,

Seok Mui Wang,

Rishya Manikam,

Chandramathi Samudi Raju,

Shamala Devi Sekaran

Publication year - 2018

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000495180

Subject(s) - herpes simplex virus , virus , endothelial stem cell , virology , biology , blood–brain barrier , cell , endothelium , transfection , cell culture , immunology , in vitro , central nervous system , genetics , neuroscience , biochemistry , endocrinology

Herpes simplex virus infection through the neuronal route is the most well-studied mode of viral encephalitis that can persists in a human host for a lifetime. However, the involvement of other possible infection mechanisms by the virus remains underexplored. Therefore, this study aims to determine the temporal effects and mechanisms by which the virus breaches the human brain micro-vascular endothelial cells of the blood-brain barrier.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research