Salusin-α Inhibits Proliferation and Migration of Vascular Smooth Muscle Cell via Akt/mTOR Signaling
Author(s) -
Shoucui Gao,
Liran Xu,
Yali Zhang,
Qingqing Yu,
Jiayan Li,
Hua Guan,
Xiaojing Wang,
Daxin Cheng,
Yi Liu,
Liang Bai,
Rong Wang,
Jianglin Fan,
Sihai Zhao,
Enqi Liu
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000494792
Subject(s) - vascular smooth muscle , pi3k/akt/mtor pathway , protein kinase b , cell growth , foam cell , phosphorylation , chemistry , aorta , immunohistochemistry , pathology , endocrinology , medicine , biology , macrophage , cancer research , signal transduction , microbiology and biotechnology , in vitro , smooth muscle , biochemistry
The proliferation and migration of vascular smooth muscle cells (VSMCs) are key steps in the progression of atherosclerosis. The aim of the present study was to investigate the potential roles of salusin-α in the functions of VSMCs during the development of atherosclerosis.
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