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Nell-1 Enhances Osteogenic Differentiation of Pre-Osteoblasts on Titanium Surfaces via the MAPK-ERK Signaling Pathway
Author(s) -
Mei-jie Shen,
Gege Wang,
Yuzhen Wang,
Jing Xie,
Xi Ding
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000494651
Subject(s) - runx2 , osteocalcin , mapk/erk pathway , alkaline phosphatase , osteoprotegerin , chemistry , osteoblast , western blot , kinase , protein kinase a , p38 mitogen activated protein kinases , osteopontin , microbiology and biotechnology , signal transduction , biochemistry , biology , enzyme , endocrinology , receptor , gene , in vitro , activator (genetics)
This study aimed to investigate the effect of Nell-1 on the osteogenic behaviors of pre-osteoblasts on titanium (Ti) surfaces and to identify the underlying signaling pathway.

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