Nell-1 Enhances Osteogenic Differentiation of Pre-Osteoblasts on Titanium Surfaces via the MAPK-ERK Signaling Pathway
Author(s) -
Mei-jie Shen,
Gege Wang,
Yuzhen Wang,
Jing Xie,
Xi Ding
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000494651
Subject(s) - runx2 , osteocalcin , mapk/erk pathway , alkaline phosphatase , osteoprotegerin , chemistry , osteoblast , western blot , kinase , protein kinase a , p38 mitogen activated protein kinases , osteopontin , microbiology and biotechnology , signal transduction , biochemistry , biology , enzyme , endocrinology , receptor , gene , in vitro , activator (genetics)
This study aimed to investigate the effect of Nell-1 on the osteogenic behaviors of pre-osteoblasts on titanium (Ti) surfaces and to identify the underlying signaling pathway.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom