Open Access2-O-Methylmagnolol Induces Apoptosis and Inhibits IL-6/STAT3 Signaling in Oral Squamous Cell Carcinoma
Author(s) -
TongHong Wang,
JiaYou Fang,
ShuJu Wu,
Yiwen Liu,
Chieh-Wen Chan,
Shih-Yi Chuang,
ChiYuan Chen
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000494474
Subject(s) - apoptosis , cancer research , basal cell , signal transduction , stat3 , chemistry , medicine , microbiology and biotechnology , biology , biochemistry
2-O-methylmagnolol (MM1), a derivative of magnolol bearing one methoxy moiety, has been shown to display improved anti-tumor activity against skin cancers. In this study, we examined the anti-tumor effects of magnolol and MM1 on oral squamous cell carcinoma (OSCC).
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