The Protective Effect of Sika Deer Antler Protein on Gentamicin-Induced Nephrotoxicity in Vitro and in Vivo | Zendy

Hang Sun | Zendy; Huihai Yang | Zendy; Haonan Ruan | Zendy; Wei Li | Zendy; Xinhong He | Zendy; Lulu Wang | Zendy; Fangfang Liu | Zendy; Jing Zhang | Zendy

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The Protective Effect of Sika Deer Antler Protein on Gentamicin-Induced Nephrotoxicity in Vitro and in Vivo

Author(s) -

Hang Sun,

Huihai Yang,

Haonan Ruan,

Wei Li,

Xinhong He,

Lulu Wang,

Fangfang Liu,

Jing Zhang

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000494471

Subject(s) - nephrotoxicity , oxidative stress , creatinine , blood urea nitrogen , viability assay , kidney , pharmacology , apoptosis , in vivo , medicine , chemistry , andrology , endocrinology , biology , biochemistry , microbiology and biotechnology

Sika deer (Cervus nippon Temminck) antler is traditional animal medicine of renal protection in East Asia. This study measured the effect of sika deer antler protein (SDAPR) on gentamicin (GM)-induced cytotoxicity in HEK293 cells, and investigated the effect of SDAPR against GM-induced nephrotoxicity in mice.

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