TGFβ1-Smad Signaling Pathway Participates in Interleukin-33 Induced Epithelial-to-Mesenchymal Transition of A549 Cells | Zendy

Qiuyue Tan | Zendy; Zhenshun Cheng | Zendy

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TGFβ1-Smad Signaling Pathway Participates in Interleukin-33 Induced Epithelial-to-Mesenchymal Transition of A549 Cells

Author(s) -

Qiuyue Tan,

Zhenshun Cheng

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000494241

Subject(s) - epithelial–mesenchymal transition , smad , a549 cell , signal transduction , transforming growth factor , western blot , cancer research , receptor , chemistry , microbiology and biotechnology , biology , endocrinology , medicine , transition (genetics) , lung , biochemistry , gene

Epithelial-to-mesenchymal transition (EMT) has been proven to be involved in development and progression of pulmonary fibrosis. This study aims to investigate the role of transforming growth factor β1 (TGFβ1)-smad signaling pathway in the interleukin-33 (IL-33) induced EMT.

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