Hypermethylation of miR-338-3p and Impact of its Suppression on Cell Metastasis Through N-Cadherin Accumulation at the Cell -Cell Junction and Degradation of MMP in Gastric Cancer
Author(s) -
Bo Guo,
Jing Zhang,
Qian Li,
Zhenghao Zhao,
Wenjing Wang,
Kaiyue Zhou,
Xiaofei Wang,
Dongdong Tong,
Lingyu Zhao,
Juan Yang,
Chen Huang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000494153
Subject(s) - microrna , cancer research , cell migration , biology , dna methylation , carcinogenesis , cell , metastasis , cancer , microbiology and biotechnology , chemistry , gene expression , gene , genetics
MicroRNAs (miRNAs) have been well studied in human carcinogenesis and cancer progression. Our previous study showed the down-regulation of miR-338-3p expression in human gastric cancer (GC). However, the reasons of this dysregulation remain largely unclear.
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