Long Non-Coding MALAT1 Functions as a Competing Endogenous RNA to Regulate Vimentin Expression by Sponging miR-30a-5p in Hepatocellular Carcinoma
Author(s) -
Yujia Pan,
Simeng Tong,
Rongjun Cui,
Jialin Fan,
Chi Liu,
Yucui Lin,
Jiebing Tang,
Hui Xie,
Ping Lin,
Tianhu Zheng,
Xiaoguang Yu
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000493962
Subject(s) - vimentin , malat1 , cancer research , blot , competing endogenous rna , adenocarcinoma , long non coding rna , metastasis , biology , hepatocellular carcinoma , real time polymerase chain reaction , cell migration , immunohistochemistry , downregulation and upregulation , cell , cancer , gene , immunology , biochemistry , genetics
Hepatocellular carcinoma (HCC) has a high morbidity as well as mortality and is believed to be one of the most prevalent cancers worldwide. The long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is involved in numerous cancers, including HCC. This study aimed to explore the role of MALAT1 in HCC progression.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom