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miRNA Expression Profile of Saliva in Subjects of Yang Deficiency Constitution and Yin Deficiency Constitution
Author(s) -
Yu Chen,
Yanling Wu,
Haiqiang Yao,
Hui Luo,
Bing Lin,
Xiuping Zhang,
Xue Liang,
Ranran Sun,
Shipeng Zhao,
Yingshuai Li,
Yanfei Zheng,
Lingru Li,
Qi Wang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000493769
Subject(s) - constitution , microrna , biology , kegg , genetics , gene , gene expression , bioinformatics , transcriptome , political science , law
Based on the theory of constitution in Traditional Chinese Medicine (TCM), the Chinese Han population has been classified into nine constitutions. Of these, Yang deficiency constitution mainly exhibit cold intolerance while Yin deficiency constitution mainly exhibit heat intolerance. Some studies have been carried out to explore the modern genetic and biological basis of such constitution classification, but more remains to be done. MicroRNA (miRNA) serves as post-transcriptional regulators of gene expression and may play a role in the classification process. Here, we examined miRNA expression profile of saliva to further improve the comprehensiveness of constitution classification.

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