Parkin Modulates ERRα/eNOS Signaling Pathway in Endothelial Cells
Author(s) -
Weiwei Xia,
Jie Yin,
Shuping Zhang,
Chu-Chu Guo,
Yuanyuan Li,
Yue Zhang,
Aihua Zhang,
Zhanjun Jia,
Hongbing Chen
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000493713
Subject(s) - parkin , enos , mitophagy , autophagy , apoptosis , microbiology and biotechnology , downregulation and upregulation , transfection , ubiquitin , chemistry , biology , endocrinology , medicine , cell culture , nitric oxide , nitric oxide synthase , biochemistry , genetics , disease , parkinson's disease , gene
Although a number of reports documented the important role of parkin in mitophagy, emerging evidence also indicated additional functions of parkin besides mitophagy. The present study was undertaken to investigate the role of parkin in the regulation of ERRα/eNOS pathway in endothelial cells (ECs).
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