FSCN1 Promotes Epithelial-Mesenchymal Transition Through Increasing Snail1 in Ovarian Cancer Cells | Zendy

Jie Li | Zendy; Songlin Zhang | Zendy; Meili Pei | Zendy; Lei Wu | Zendy; Yanli Liu | Zendy; Huijin Li | Zendy; Jiaojiao Lu | Zendy; Xu Li | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

FSCN1 Promotes Epithelial-Mesenchymal Transition Through Increasing Snail1 in Ovarian Cancer Cells

Author(s) -

Jie Li,

Songlin Zhang,

Meili Pei,

Lei Wu,

Yanli Liu,

Huijin Li,

Jiaojiao Lu,

Xu Li

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000493622

Subject(s) - epithelial–mesenchymal transition , ovarian cancer , vimentin , metastasis , cancer research , downregulation and upregulation , cancer , biology , cancer cell , oncology , medicine , immunology , immunohistochemistry , gene , biochemistry

Epithelial-mesenchymal transition (EMT) is one of the key mechanisms mediating cancer progression. Snail1 has a pivotal role in the regulation of EMT, involving the loss of E-cadherin and concomitant upregulation of vimentin, among other biomarkers. We have found FSCN1 promoted EMT in ovarian cancer cells, but the precise mechanism of FSCN1 in EMT process has not been clearly elucidated.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research