Cardiac Shock Wave Therapy Attenuates Cardiomyocyte Apoptosis after Acute Myocardial Infarction in Rats | Zendy

Yunhe Zhang | Zendy; Tao Shen | Zendy; Bing Liu | Zendy; DaPeng Dai | Zendy; Jianping Cai | Zendy; Cong Zhao | Zendy; Ling Du | Zendy; Na Jia | Zendy; Qing He | Zendy

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Cardiac Shock Wave Therapy Attenuates Cardiomyocyte Apoptosis after Acute Myocardial Infarction in Rats

Author(s) -

Yunhe Zhang,

Tao Shen,

Bing Liu,

DaPeng Dai,

Jianping Cai,

Cong Zhao,

Ling Du,

Na Jia,

Qing He

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000493616

Subject(s) - apoptosis , medicine , myocardial infarction , inflammation , cardiology , cardiac function curve , ligation , tunel assay , in vivo , ventricular remodeling , heart failure , chemistry , biology , immunohistochemistry , biochemistry , microbiology and biotechnology

Researches have showed that cardiac shock wave therapy (CSWT) could improve left ventricular function and attenuate LV remodeling of the ischemic heart. Apoptosis plays an important role in myocardial infarction and determines heart function and prognosis. However, it is still not clear whether CSWT is sufficient to attenuate acute myocardial infarction (AMI) induced cardiomyocyte apoptosis in vivo. In this study, we used a rat model to examine whether CSWT could attenuate cardiomyocyte apoptosis after AMI and to explore potential mechanisms.

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