Genome-Wide Network-Based Analysis of Colorectal Cancer Identifies Novel Prognostic Factors and an Integrative Prognostic Index | Zendy

Xiaolin Hou | Zendy; Xuelai He | Zendy; Kang Wang | Zendy; Nengyi Hou | Zendy; Junwen Fu | Zendy; Guiqing Jia | Zendy; Xiaofei Zuo | Zendy; Haibo Xiong | Zendy; Minghui Pang | Zendy

Open Access

Genome-Wide Network-Based Analysis of Colorectal Cancer Identifies Novel Prognostic Factors and an Integrative Prognostic Index

Author(s) -

Xiaolin Hou,

Xuelai He,

Kang Wang,

Nengyi Hou,

Junwen Fu,

Guiqing Jia,

Xiaofei Zuo,

Haibo Xiong,

Minghui Pang

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000493614

Subject(s) - colorectal cancer , cancer , medicine , oncology , genome , biology , computational biology , gene , genetics

Colorectal cancer (CRC) is one of leading cancers in both incidence and mortality rate. The 5-year survival rate varies considerably depending on the pathological stage of the tumor. Although prominent progress has been made through screening for survival-associated factors from a certain type of genetic or epigenetic modifications, few attempts have been made to apply a network-based approach in prognostic factor identification, which could prove valuable for a complex, multi-faceted disease such as CRC.

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