Towards a Regional Registry of Extended Typed Blood Donors: Molecular Typing for Blood Group, Platelet and Granulocyte Antigens | Zendy

Jan Portegys | Zendy; Gabi Rink | Zendy; Pia Bloos | Zendy; Erwin A. Scharberg | Zendy; Harald Klüter | Zendy; Peter Bugert | Zendy

Open Access

Towards a Regional Registry of Extended Typed Blood Donors: Molecular Typing for Blood Group, Platelet and Granulocyte Antigens

Author(s) -

Jan Portegys,

Gabi Rink,

Pia Bloos,

Erwin A. Scharberg,

Harald Klüter,

Peter Bugert

Publication year - 2018

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000493555

Subject(s) - abo blood group system , allele , antigen , immunology , genotype , human leukocyte antigen , histocompatibility testing , biology , medicine , allele frequency , genetics , gene

The provision of compatible blood products to patients is the most essential task of transfusion medicine. Besides ABO and Rh, a number of additional blood group antigens often have to be considered for the blood supply of immunized or chronically transfused patients. It also applies for platelet antigens (HPA) and neutrophil antigens (HNA) for patients receiving platelet or granulocyte concentrates. Here, we describe the molecular screening for a number of blood group, HPA, and HNA alleles. Based on the screening results we are building up a regional blood donor registry to provide extended matched blood products on demand.

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