Cervical and Amniotic Fluid Matrix Metalloproteinase-8 and Interleukin-6 Concentrations in Preterm Pregnancies with or without Preterm Premature Rupture of Membranes | Zendy

Emilia Holmström | Zendy; Tarja Myntti | Zendy; Timo Sorsa | Zendy; Heidi Kruit | Zendy; Juuso Juhila | Zendy; Jorma Paavonen | Zendy; Leena Rahkonen | Zendy; Vedran Stefanović | Zendy

Open Access

Cervical and Amniotic Fluid Matrix Metalloproteinase-8 and Interleukin-6 Concentrations in Preterm Pregnancies with or without Preterm Premature Rupture of Membranes

Author(s) -

Emilia Holmström,

Tarja Myntti,

Timo Sorsa,

Heidi Kruit,

Juuso Juhila,

Jorma Paavonen,

Leena Rahkonen,

Vedran Stefanović

Publication year - 2018

Publication title -

fetal diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.976

H-Index - 60

eISSN - 1421-9964

pISSN - 1015-3837

DOI - 10.1159/000493207

Subject(s) - amniocentesis , medicine , amniotic fluid , gestation , premature rupture of membranes , cervical cerclage , obstetrics , cervical insufficiency , gestational age , fetus , pregnancy , gynecology , matrix metalloproteinase 3 , chorioamnionitis , gastroenterology , matrix metalloproteinase , prenatal diagnosis , cervix , genetics , cancer , biology

Intra-amniotic inflammation is defined by elevated inflammatory biomarkers in the amniotic fluid (AF), either due to microbial invasion of the amniotic cavity (MIAC) or sterile inflammation. Amniocentesis being an invasive procedure, we wanted to investigate whether elevated matrix metalloproteinase-8 (MMP-8) or interleukin-6 (IL-6) concentrations could be detected from cervical fluid samples.

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