MKRN3 Levels in Girls with Central Precocious Puberty during GnRHa Treatment: A Longitudinal Study | Zendy

Anna Grandone | Zendy; Grazia Cirillo | Zendy; Marcella Sasso | Zendy; Gianluca Tornese | Zendy; Caterina Luongo | Zendy; Adalgisa Festa | Zendy; Pierluigi Marzuillo | Zendy; Emanuele Miraglia del Giudice | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

MKRN3 Levels in Girls with Central Precocious Puberty during GnRHa Treatment: A Longitudinal Study

Author(s) -

Anna Grandone,

Grazia Cirillo,

Marcella Sasso,

Gianluca Tornese,

Caterina Luongo,

Adalgisa Festa,

Pierluigi Marzuillo,

Emanuele Miraglia del Giudice

Publication year - 2018

Publication title -

hormone research in paediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.816

H-Index - 89

eISSN - 1663-2826

pISSN - 1663-2818

DOI - 10.1159/000493134

Subject(s) - medicine , central precocious puberty , endocrinology , precocious puberty , basal (medicine) , hormone , insulin

Recently, mutations of makorin RING finger protein 3 (MKRN3) have been identified in familial central precocious puberty (CPP). Serum levels of this protein decline before the pubertal onset in healthy girls and boys and are lower in patients with CPP compared to prepubertal matched pairs. The aim of our study was to investigate longitudinal changes in circulating MKRN3 levels in patients with CPP before and during GnRH analogs (GnRHa) treatment.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research