Arctigenin Attenuates Ischemia/Reperfusion Induced Ventricular Arrhythmias by Decreasing Oxidative Stress in Rats | Zendy

Jing Yang | Zendy; HongShan Yin | Zendy; Yajing Cao | Zendy; Zhian Jiang | Zendy; Yongjun Li | Zendy; Mu-chun Song | Zendy; YongFei Wang | Zendy; Zhihua Wang | Zendy; Rong Yang | Zendy; Yunfa Jiang | Zendy; JinPeng Sun | Zendy; Boyi Liu | Zendy; Chuan Wang | Zendy

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Arctigenin Attenuates Ischemia/Reperfusion Induced Ventricular Arrhythmias by Decreasing Oxidative Stress in Rats

Author(s) -

Jing Yang,

HongShan Yin,

Yajing Cao,

Zhian Jiang,

Yongjun Li,

Mu-chun Song,

YongFei Wang,

Zhihua Wang,

Rong Yang,

Yunfa Jiang,

JinPeng Sun,

Boyi Liu,

Chuan Wang

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000493038

Subject(s) - malondialdehyde , medicine , ventricular fibrillation , ventricular tachycardia , superoxide dismutase , oxidative stress , ischemia , glutathione peroxidase , myocardial infarction , cardiology , anesthesia , pharmacology

Arctigenin (ATG) has been shown to possess anti-inflammatory, immunemodulatory, anti-viral, anti-microbial, anti-carcinogenic, vasodilatory and anti-platelet aggregation properties. However, the protective role of ATG in prevention of arrhythmias induced by myocardial ischemia/reperfusion is unknown. The aim of this study was to investigate the anti-arrhythmia effect of ATG in an ischemia/reperfusion injured rat heart model and explore the related mechanisms.

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