Effects of the Calcium-Activated Chloride Channel Inhibitors T16Ainh-A01 and CaCCinh-A01 on Cardiac Fibroblast Function | Zendy

Xiangqin Tian | Zendy; Ketao Ma | Zendy; Xianwei Wang | Zendy; Yang Wang | Zendy; Zhikun Guo | Zendy; JunQiang Si | Zendy

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Effects of the Calcium-Activated Chloride Channel Inhibitors T16Ainh-A01 and CaCCinh-A01 on Cardiac Fibroblast Function

Author(s) -

Xiangqin Tian,

Ketao Ma,

Xianwei Wang,

Yang Wang,

Zhikun Guo,

JunQiang Si

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000493036

Subject(s) - intracellular , calcium in biology , cell migration , chemistry , microbiology and biotechnology , extracellular , secretion , cell growth , chloride channel , cell , biochemistry , biology

Calcium-activated chloride channels (CaCCs) regulate numerous physiological processes including cell proliferation, migration, and extracellular matrix secretion. T16Ainh-A01 and CaCCinh-A01 are selective inhibitors of CaCCs. But it is unknown whether these two compounds have functional effects on cardiac fibroblasts (CFs).

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