Local Delivery of β-Elemene Improves Locomotor Functional Recovery by Alleviating Endoplasmic Reticulum Stress and Reducing Neuronal Apoptosis in Rats with Spinal Cord Injury | Zendy

Jingyu Wang | Zendy; Heyangzi Li | Zendy; Yucheng Ren | Zendy; Ying Yao | Zendy; Jue Hu | Zendy; Mingzhi Zheng | Zendy; Yuemin Ding | Zendy; Yingying Chen | Zendy; YueLiang Shen | Zendy; LinLin Wang | Zendy; Yongjian Zhu | Zendy

Open Access

Local Delivery of β-Elemene Improves Locomotor Functional Recovery by Alleviating Endoplasmic Reticulum Stress and Reducing Neuronal Apoptosis in Rats with Spinal Cord Injury

Author(s) -

Jingyu Wang,

Heyangzi Li,

Yucheng Ren,

Ying Yao,

Jue Hu,

Mingzhi Zheng,

Yuemin Ding,

Yingying Chen,

YueLiang Shen,

LinLin Wang,

Yongjian Zhu

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000492996

Subject(s) - nissl body , tunel assay , viability assay , apoptosis , terminal deoxynucleotidyl transferase , neuroprotection , propidium iodide , pi3k/akt/mtor pathway , biology , caspase 3 , programmed cell death , microbiology and biotechnology , chemistry , pharmacology , biochemistry , staining , genetics

Spinal cord injury (SCI) is a serious global problem that leads to permanent motor and sensory deficits. This study explores the anti-apoptotic and neuroprotective effects of the natural extract β-elemene in vitro and in a rat model of SCI.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research