Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-β1/ADAMTS-1 Signaling Pathway
Author(s) -
Hao Liu,
Yi He,
Zhaolei Jiang,
Saie Shen,
Mei Ju,
Min Tang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000492989
Subject(s) - pulmonary fibrosis , hydroxyproline , bronchoalveolar lavage , prodigiosin , lung , fibrosis , pathology , fibroblast , medicine , viability assay , chemistry , cell , in vitro , biochemistry , escherichia coli , gene , serratia marcescens
Pulmonary fibrosis is a common outcome of various interstitial lung diseases. Prodigiosin (PG) is a series of red pigment with methoxypyrrole ring. This studyinvestigates therole of prodigiosin in pulmonary fibrosis and its underlying mechanisms.
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