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Prevalence and Prognostic Significance of HPV in Laryngeal Squamous Cell Carcinoma in Northeast China
Author(s) -
Fangjia Tong,
Jingshu Geng,
Bingqing Yan,
Huihuang Lou,
Xiaohang Chen,
Chenwei Duan,
Jing He,
Siwei Zhang,
Huanhuan Xie,
Huining Li,
Dawei Yuan,
Fengmin Zhang,
Hongxue Meng,
Lanlan Wei
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000492858
Subject(s) - medicine , hazard ratio , oncology , immunohistochemistry , larynx , hpv infection , confidence interval , polymerase chain reaction , cancer , pathology , cervical cancer , gene , biology , biochemistry , surgery
Human papillomavirus (HPV) is an etiological risk factor for a subset of head and neck squamous cell carcinomas. HPV has been proven to be a powerful prognostic biomarker for oropharyngeal cancer, but its role in the larynx has not been explored in depth. Here, we sought to evaluate the prevalence and genotype distribution of HPV in patients with laryngeal squamous cell carcinoma (LSCC) in northeast China.

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