Long Non-Coding RNA MEG3 Functions as a Competing Endogenous RNA to Regulate HOXA11 Expression by Sponging miR-181a in Multiple Myeloma
Author(s) -
Xuxing Shen,
Hua Bai,
Huayuan Zhu,
Qing Yan,
Ye Yang,
Wenjun Yu,
Qinglin Shi,
Juejin Wang,
Jianyong Li,
Lijuan Chen
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000492846
Subject(s) - meg3 , competing endogenous rna , long non coding rna , rna , cancer research , biology , gene expression , flow cytometry , tumor progression , microrna , in vivo , regulation of gene expression , gene , microbiology and biotechnology , biochemistry , genetics
Long non-coding RNA maternally expressed gene 3 (MEG3) has been reported to play an essential role in cancer progression and metastasis. However, the overall biological role and regulatory mechanism of MEG3 in multiple myeloma (MM) development and progression remains largely ill-defined.
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