Evidence of Decreased Activity in Intermediate-Conductance Calcium-Activated Potassium Channels During Retinoic Acid–Induced Differentiation in Motor Neuron–Like NSC-34 Cells | Zendy

PeiChun Chen | Zendy; JingSyuna Ruan | Zendy; ShengNan Wu | Zendy

Open Access

Evidence of Decreased Activity in Intermediate-Conductance Calcium-Activated Potassium Channels During Retinoic Acid–Induced Differentiation in Motor Neuron–Like NSC-34 Cells

Author(s) -

PeiChun Chen,

JingSyuna Ruan,

ShengNan Wu

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000492653

Subject(s) - retinoic acid , potassium channel , electrophysiology , chemistry , microbiology and biotechnology , calcium activated potassium channel , cellular differentiation , patch clamp , potassium channel blocker , ion channel , biophysics , biology , endocrinology , medicine , biochemistry , neuroscience , receptor , gene

Intermediate-conductance Ca2+-activated K+ (IKCa; KCa3.1 or KCNN4) channels affect the behaviors of central neurons including motor neurons. The mechanism through which neuronal differentiation is related to the activity of these channels remains largely unclear.

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