miRNA-125b Regulates Osteogenic Differentiation of Periodontal Ligament Cells Through NKIRAS2/NF-κB Pathway
Author(s) -
Xue Nan,
Lin Qi,
Guorong Zhang,
Yang Zhang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000492350
Subject(s) - osteoblast , microrna , microbiology and biotechnology , cellular differentiation , chemistry , runx2 , periodontal fiber , western blot , regulator , alkaline phosphatase , luciferase , signal transduction , transfection , biology , gene , in vitro , medicine , biochemistry , dentistry , enzyme
Osteogenesis of periodontal ligament cells (PDLCS) is essential for alveolar bone repair. Varieties of factors have been found involved in the regulation of PDLCs osteoblast differentiation. Aim of this study was to identify microRNA as a regulator of the os-teogenic differentiation of PDLCs.
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