Open AccessInhibition of ITCH Suppresses Proliferation and Induces Apoptosis of Lung Cancer Cells
Author(s) -
Pengfei Li,
Qi-Gang Zhang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000492295
Subject(s) - lung cancer , apoptosis , cancer research , cancer , mmp2 , cell growth , western blot , mmp9 , mtt assay , cancer cell , biology , medicine , pathology , metastasis , downregulation and upregulation , biochemistry , genetics , gene
The E3 ubiquitin ligase ITCH plays an important role in invasive and metastatic cancers. However, the role of ITCH in the progression of lung cancer has not been fully described.
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