Long Non-Coding RNA LINC01260 Inhibits the Proliferation, Migration and Invasion of Spinal Cord Glioma Cells by Targeting CARD11 Via the NF-κB Signaling Pathway
Author(s) -
DongMei Wu,
XinRui Han,
Xin Wen,
Shan Wang,
YongJian Wang,
Min Shen,
ShaoHua Fan,
Juan Zhuang,
Zi-Feng Zhang,
Qun Shan,
MengQiu Li,
Bin Hu,
Chunhui Sun,
Jun Lü,
YuanLin Zheng
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000492279
Subject(s) - glioma , cancer research , biology , viability assay , cell growth , flow cytometry , apoptosis , microbiology and biotechnology , biochemistry , genetics
Spinal cord glioma is a highly aggressive malignancy that commonly results in high mortality due to metastasis, high recurrence and limited treatment regimens. This study aims to elucidate the effects of long non-coding RNA LINC01260 (LINC01260) on the proliferation, migration and invasion of spinal cord glioma cells by targeting Caspase recruitment domain family, member 11 (CARD11) via nuclear factor kappa B (NF-κB) signaling.
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