Ergosterol Attenuates LPS-Induced Myocardial Injury by Modulating Oxidative Stress and Apoptosis in Rats
Author(s) -
Jianjun Xu,
Cai Lin,
Tingting Wang,
Peng Zhang,
Zhengjun Liu,
Caijiao Lu
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000491887
Subject(s) - oxidative stress , superoxide dismutase , apoptosis , malondialdehyde , chemistry , lactate dehydrogenase , lipopolysaccharide , pharmacology , cytochrome c , microbiology and biotechnology , biology , biochemistry , endocrinology , enzyme
Ergosterol (ER) is the primary sterol found in fungi and is named after the ergot fungus. A variety of pharmacological activities have been reported for ER, including antioxidative, anti-proliferative, and anti-inflammatory effects, although its role in sepsis remains unclear.
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