Salivary Circular RNAs Hsa_Circ_0001874 and Hsa_Circ_0001971 as Novel Biomarkers for the Diagnosis of Oral Squamous Cell Carcinoma
Author(s) -
Siyu Zhao,
Jun Wang,
Shaobo Ouyang,
Zikun Huang,
Lan Liao
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000491624
Subject(s) - circular rna , saliva , receiver operating characteristic , basal cell , stage (stratigraphy) , downregulation and upregulation , microarray , immunohistochemistry , cancer research , biology , medicine , gene , gene expression , genetics , paleontology
Recent studies have demonstrated that circular RNAs (circRNAs) can serve as potential molecular markers for disease diagnosis. However, little is known about their diagnostic potential for oral squamous cell carcinoma (OSCC). This study aimed to determine the expression of circRNAs in the saliva of OSCC patients to identify novel biomarkers for OSCC screening.
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