Biochemical and Molecular Mechanisms of Platelet-Rich Plasma in Ameliorating Liver Fibrosis Induced by Dimethylnitrosurea | Zendy

Neveen A. Salem | Zendy; Amal H. Hamza | Zendy; Hanan S. Alnahdi | Zendy; Najla O. Ayaz | Zendy

Open Access

Biochemical and Molecular Mechanisms of Platelet-Rich Plasma in Ameliorating Liver Fibrosis Induced by Dimethylnitrosurea

Author(s) -

Neveen A. Salem,

Amal H. Hamza,

Hanan S. Alnahdi,

Najla O. Ayaz

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000491544

Subject(s) - liver fibrosis , fibrosis , platelet rich plasma , cancer research , chemistry , platelet , medicine , microbiology and biotechnology , endocrinology , pharmacology , biology

Hepatic fibrosis is a wound-healing process in the chronically injured liver. Clinical application of platelet-rich plasma (PRP) is of considerable interest for wound healing and regeneration. In view of the regeneration effect of PRP, we designed this study to explore the hypothesis that PRP could play a role in improving the biochemical and molecular changes that occur in liver fibrosis induced by dimethylnitrosamine (DMN) in rats.

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