Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism | Zendy

Mary Ellen Vajravelu | Zendy; Morgan Congdon | Zendy; Lauren Mitteer | Zendy; Jamie Koh | Zendy; Stephanie Givler | Zendy; Justine Shults | Zendy; Diva D. De León | Zendy

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Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism

Author(s) -

Mary Ellen Vajravelu,

Morgan Congdon,

Lauren Mitteer,

Jamie Koh,

Stephanie Givler,

Justine Shults,

Diva D. De León

Publication year - 2018

Publication title -

hormone research in paediatrics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.816

H-Index - 89

eISSN - 1663-2826

pISSN - 1663-2818

DOI - 10.1159/000491105

Subject(s) - medicine , discontinuation , adverse effect , hypoglycemia , pediatrics , retrospective cohort study , immunoglobulin d , congenital hyperinsulinism , body mass index , refractory (planetary science) , gastroenterology , hyperinsulinism , insulin , insulin resistance , b cell , astrobiology , antibody , immunology , physics

Feeding problems are frequent in infants with congenital hyperinsulinism (HI) and may be exacerbated by continuous enteral nutrition (EN) used to maintain euglycemia. Our center's HI team uses dextrose solution given continuously via gastric tube (intrasgastric dextrose, IGD) for infants not fully responsive to conventional medical therapy or pancreatectomy. Here, we describe our practice as well as growth, feeding, and adverse events in infants with HI exposed to IGD.

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