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Induced Pluripotent Stem Cell Transplantation Improves Locomotor Recovery in Rat Models of Spinal Cord Injury: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Author(s) -
Chuan Qin,
Yun Guo,
Degang Yang,
Mingliang Yang,
Liangjie Du,
Jianjun Li
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000491064
Subject(s) - spinal cord injury , medicine , induced pluripotent stem cell , transplantation , meta analysis , spinal cord , randomized controlled trial , stem cell , neuroscience , biology , embryonic stem cell , pathology , surgery , microbiology and biotechnology , biochemistry , gene
Spinal cord injury (SCI) has long been a subject of great interest in a wide range of scientific fields. Several attempts have been made to demonstrate motor function improvement in rats with SCI after transplantation of induced pluripotent stem cells (iPSC). This systematic review and meta-analysis was designed to summarize the effects of iPSC on locomotor recovery in rat models of SCI.

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