Open AccessGenistein Enhances or Reduces Glycosaminoglycan Quantity in a Cell Type-Specific Manner
Author(s) -
Ying Lan,
Xiulian Li,
Xuebo Liu,
Cui Hao,
Song Ni,
Sumei Ren,
Wei Wang,
Ningchuan Feng,
Lijuan Zhang
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000490985
Subject(s) - genistein , glycosaminoglycan , microbiology and biotechnology , cell type , cell , chemistry , biochemistry , biology , endocrinology
Genistein is a natural isoflavone enriched in soybeans. It has beneficial effects for patients with mucopolysaccharidose type III through inhibiting glycosaminoglycan biosynthesis. However, other studies indicate that genistein does not always inhibit glycosaminoglycan biosynthesis.
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