Sensitization of Gastric Cancer Cells to 5-FU by MicroRNA-204 Through Targeting the TGFBR2-Mediated Epithelial to Mesenchymal Transition | Zendy

Liangqing Li | Zendy; Dun Pan | Zendy; Qun Chen | Zendy; Shengwei Zhang | Zendy; Diya Xie | Zendy; Xuelan Zheng | Zendy; Hui Chen | Zendy

Open Access

Sensitization of Gastric Cancer Cells to 5-FU by MicroRNA-204 Through Targeting the TGFBR2-Mediated Epithelial to Mesenchymal Transition

Author(s) -

Liangqing Li,

Dun Pan,

Qun Chen,

Shengwei Zhang,

Diya Xie,

Xuelan Zheng,

Hui Chen

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000490871

Subject(s) - epithelial–mesenchymal transition , microrna , downregulation and upregulation , cancer research , western blot , cell culture , mesenchymal stem cell , cell growth , biology , cancer , microbiology and biotechnology , mtt assay , chemistry , gene , biochemistry , genetics

Gastric cancer (GC) is the most common gastrointestinal malignancy, causing cancer-related deaths in East Asia. MicroRNAs (miRNAs) are small non-coding RNAs aberrantly expressed in human tumors. In this study, we aim to investigate the roles of miR-204 in the epithelial to mesenchymal transition (EMT)-associated chemosensitivity.

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