Thymic Stromal Lymphopoietin Signaling Pathway Inhibition Attenuates Airway Inflammation and Remodeling in Rats with Asthma | Zendy

Zhe Cheng | Zendy; Wang Xi | Zendy; Lingling Dai | Zendy; Liuqun Jia | Zendy; Xiaogang Jing | Zendy; Ying Liu | Zendy; Huan Wang | Zendy; Pengfei Li | Zendy; Lin An | Zendy; Meng Liu | Zendy

Open Access

Thymic Stromal Lymphopoietin Signaling Pathway Inhibition Attenuates Airway Inflammation and Remodeling in Rats with Asthma

Author(s) -

Zhe Cheng,

Wang Xi,

Lingling Dai,

Liuqun Jia,

Xiaogang Jing,

Ying Liu,

Huan Wang,

Pengfei Li,

Lin An,

Meng Liu

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000490865

Subject(s) - thymic stromal lymphopoietin , ovalbumin , bronchoalveolar lavage , immunology , asthma , inflammation , medicine , allergic inflammation , cytokine , immune system , lung

Thymic stromal lymphopoietin (TSLP) is a cytokine that plays diverse roles in the regulation of immune responses. However, a detailed understanding of the TSLP signaling pathway in asthma remains elusive. In this study, we aimed to investigate the role of the TSLP signaling pathway in asthma and its effect on airway inflammation and remodeling.

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