Induction of Pro-Inflammatory Response via Activated Macrophage-Mediated NF-κB and STAT3 Pathways in Gastric Cancer Cells
Author(s) -
Yujuan Zhou,
Longzheng Xia,
Qiang Liu,
Heran Wang,
Jingguan Lin,
Linda Oyang,
Xiaohong Chen,
Xia Luo,
Shiming Tan,
Yutong Tian,
Min Su,
Ying Wang,
Pan Chen,
Yang Wu,
Hui Wang,
Qianjin Liao
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000490829
Subject(s) - cancer , cancer research , inflammation , stat3 , cancer cell , carcinogenesis , immunohistochemistry , gastric mucosa , cell growth , chemistry , medicine , apoptosis , immunology , stomach , biochemistry
Chronic inflammation plays an important role in the initiation and progression of gastric cancer (GC). However, the role and relationship of activated macrophages with gastric mucous epithelium cells in initiating and maintaining the inflammatory process during gastric carcinogenesis remains unclear.
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