Clinical Implication of Multi-Parameter Flow Cytometry in Myelodysplastic Syndromes | Zendy

Carolien Duetz | Zendy; Theresia M. Westers | Zendy; Arjan A. van de Loosdrecht | Zendy

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Clinical Implication of Multi-Parameter Flow Cytometry in Myelodysplastic Syndromes

Author(s) -

Carolien Duetz,

Theresia M. Westers,

Arjan A. van de Loosdrecht

Publication year - 2018

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000490727

Subject(s) - myelodysplastic syndromes , flow cytometry , risk stratification , medicine , disease , intensive care medicine , immunology , oncology , pathology , bone marrow

Myelodysplastic syndromes (MDS) are a challenging group of diseases for clinicians and researchers, as both disease course and pathobiology are highly heterogeneous. In (suspected) MDS patients, multi-parameter flow cytometry can aid in establishing diagnosis, risk stratification and choice of therapy. This review addresses the developments and future directions of multi-parameter flow cytometry scores in MDS. Additionally, we propose an integrated diagnostic algorithm for suspected MDS.

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